Orbital shaken benchtop bioreactors / fermentors - SB10-X

The SB10-X is an orbital shaken benchtop bioreactor system for the cultivation of human, mammalian and plant cells in a single-use bag. It consists of six modules (excluding the bag) and has a working volume from 4 liters up to 12 liters.

The SB10-X can be used in research, process development or as a pilot-scale bioreactor. The orbital motion of the SB10-X ensures efficient liquid mixing. It facilitates high oxygen transfer rates with low shear forces. Mechanical stress on the cells is reduced thanks to bubble-free surface gassing with almost no frothing. This motion is particularly suitable for microcarrier cultivation. The SB10-X uses the robust Kuhner direct drive which provides accurate control of the orbital speed.

Performance characteristics:

• Cultivation of human, mammalian and plant cells
• Fast, simple set up
• Easy scale-up
• Online measurement and control of pH and DO
• Three different types of single-use bags available

The SB10-X fills a gap in the scale-up chain from commonly used single-use flasks up to 50 liter and 200 liter bioreactors. The consistent hydrodynamics of shaken bioreactors provide reproducible cultivation conditions throughout the volume range. The culture from the SB10-X can serve as a preculture for the SB50-X and SB200-X Orbital Shakers.