Spray dried biodegradable polymers as target material for controlled drug delivery
Biodegradable polymers based on polylactide (PLA) and its co-polymers polylactide-co-glycolide (PLGA) were successfully spray dried with the Mini Spray Dryer B-290. Process parameters are found to prepare spherical particles with a smooth or structured surface.
A literature review demonstrates the feasibility to encapsulate different drugs in biodegradable microspheres for controlled drug delivery systems. Spray dried microparticles have a suitable size and shape for new application fields in pulmonary therapy, cancer treatment or medical devices.
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